Twistronics has become a new alchemy of materials. By choosing atomically thin layers, stacking them and changing their relative angle, researchers can create electronic behavior absent from the original ingredients. Twisted graphene and transition metal dichalcogenides have already yielded superconductivity and fractional Chern insulators, states with fractionally charged excitations. One of physics’ most active frontiers now has a moonshot ambition: to design entirely new forms of quantum matter.